MOTS-c is a mitochondrial-derived peptide studied for its role in how cells adapt, regulate, and optimize energy under metabolic stress. This research peptide is frequently used in laboratory models focused on insulin sensitivity, glucose metabolism, and mitochondrial signaling pathways.
 
MOTS-c is encoded within the mitochondrial genome, placing it in a unique class of signaling peptides that directly connect mitochondrial activity with nuclear gene expression. Rather than acting on a single pathway, it is studied for how it influences broader systems involved in energy balance, metabolic efficiency, and cellular resilience.
 
Mechanism of Action
 
MOTS-c is studied for its role in coordinating metabolic signaling and cellular adaptation pathways.
Research has explored associations with:
 
• Activation of AMPK, a central regulator of cellular energy balance
• Increased glucose uptake and improved insulin signaling response
• Promotion of fatty acid utilization and metabolic efficiency
• Support for cellular adaptation during metabolic and oxidative stress
• Modulation of pathways involved in mitochondrial-to-nuclear communication
 
Research Applications
 
MOTS-c is commonly studied in laboratory settings involving:
 
• Metabolic function and energy regulation research
• Insulin sensitivity and glucose utilization studies
• Mitochondrial signaling and cellular adaptation models
• Exercise physiology and metabolic stress response research
• Aging and cellular resilience pathways
 
Product Specifications
 
• Peptide Content: 5mg Lyophilized Peptide
• Structure: Mitochondrial-Derived Peptide (MDP)
• Purity: ≥98% verified by HPLC testing
• Form: Lyophilized peptide powder
• Storage: Store lyophilized peptide frozen. After reconstitution, maintain refrigerated conditions (2–8°C) and avoid repeated freeze-thaw cycles.
 
Research Use Notice
 
This product is intended strictly for laboratory research and analytical purposes only.
 
• Not for human consumption
• Not for veterinary use
• Not intended for ingestion, injection, or bodily administration
• Not a drug, food, cosmetic, or dietary supplement
 
All information provided is for educational and scientific reference purposes only.