Melanotan-2 is a synthetic melanocortin analog commonly studied in laboratory models involving melanin production, melanocortin receptor signaling, and pigmentation pathways. This research peptide is frequently used in experimental settings focused on melanogenesis, photobiology, and neuroendocrine signaling.
 
Melanotan-2 is a cyclic peptide designed to interact with melanocortin receptors, particularly MC1R, which plays a central role in melanin synthesis. Its stability and receptor affinity make it a widely studied compound in models exploring pigmentation mechanisms and melanocortin system activity.
 
Mechanism of Action
 
Melanotan-2 is studied for its interaction with melanocortin receptors (MC1R–MC5R), influencing pigmentation and related signaling pathways.
 
Research has explored associations with:
 
• Activation of MC1R supporting melanin production (melanogenesis)
• Modulation of melanocyte activity and pigmentation pathways
• Interaction with melanocortin receptors involved in neuroendocrine signaling
• Support for UV-independent pigmentation modeling
• Engagement with pathways related to appetite and behavioral signaling in research models
 
Research Applications
 
Melanotan-2 is commonly studied in laboratory settings involving:
 
• Pigmentation and melanogenesis research
• Photobiology and UV-response pathway studies
• Melanocyte signaling and skin biology models
• Neuroendocrine and melanocortin system research
 
Product Specifications
 
• Peptide Content: 10mg Lyophilized Peptide
• Sequence: Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂
• Molecular Weight: ~1024.2 g/mol
• Purity: ≥98% verified by HPLC testing
• Form: Lyophilized peptide powder
• Storage: Store lyophilized peptide frozen. After reconstitution, maintain refrigerated conditions (2–8°C) and avoid repeated freeze-thaw cycles.
 
Research Use Notice
 
This product is intended strictly for laboratory research and analytical purposes only.
 
• Not for human consumption
• Not for veterinary use
• Not intended for ingestion, injection, or bodily administration
• Not a drug, food, cosmetic, or dietary supplement
 
All information provided is for educational and scientific reference purposes only.